Predicting Every Spike

Predicting Every Spike A Model for the Responses of Visual Neurons

In the early visual system, neuronal responses can be extremely precise. Under a wide range of stimuli, cells in the retina and thalamus fire spikes very reproducibly, often with millisecond precision on subsequent stimulus repeats. Here we develop a mathematical description of the firing process that, given the recent visual input, accurately predicts the timing of individual spikes. The forma...

Chapter 1 Can We Predict Every Spike ?

Is it possible to predict the spike times of a neuron with millisecond precision? In the classical picture of rate coding (Adrian, 1928), single spikes do not play a role, and the question would have to be answered negatively. For rate coding in a singleneuron, the relevant quantity to encode a stimulus such as pressure onto a touch sensor in the skin (Adrian, 1928) or presence of a light bar i...

Sensation - targeted motor control : Every spike counts ?

Traditionally, sensory processing and motor control have been studied separately, reflecting the belief that sensory and motor streams remain independent until linked via cortical “associative” areas. Although this belief no longer dominates neuroscience, the traditional tendency to continue to study sensory processing and motor control separately is not easily overcome. Only after closely exam...

Predicting Spike Train Responses of Neuron Models Predicting Spike Train Responses of Neuron Models

It is shown how neural spike train responses can be predicted by truncated Wiener series and by LN-cascade models. To prove the capability of these methods we test them on spike trains which have been generated by model neurons. The agreement of the approximated responses and the neuron response to known stimuli is analysed quantitatively by calculating least mean square errors and rates of coi...

Predicting spike train responses of neuron models